osteomylitis

Hi sesapa yg terbaca blog nih. Sorila kalo entry nih merapu sebab kengkadang nih la tempat ak nak meluahkan rasa. Rasa payau , masin dsb.

So today i want to merepek bout osteomylitis. So wut do u understand bout osteomyelitis? What is the meaning? The inflammation of the bone and cartilage.
Ingat tu bukan bjne jer tau sbb word 'mye' to refer to the cartilage.

So usually the route of infection are hematogenous, thru wound fracture, ape lg ek? Aa..
Extension of the infection like septic arthritis.

So this infection start from the metaphyseal region. Why? High vascularity there. So when there is bacterial infection. It will lead to inflammatory response and promote release other mediators to. So this will cause swelling and edema of the area. High pressure in that area causing the congestion and lead to ischemic. Part nih ak plik skit. Bile dah congestion naper ischemic plak? Btul ker notes nih? Ah it doesnt matter as long i just explain wut i noe.

So what happen next? Tjen it will cause cell necrosis and it will extend to the periosteum and create subperiosteal abscess.

So in persistent infection the inflammation reaction will increase the fibroblast activity. As healing process la kirenyer sbb formation of fibrin usually occur after inflammation. So if u see inflammation tmpat tu juge ade fibrosis activity. Anyway lets proceed. So there are also increased in osteoblastic activity and osteclastic activity.

So osteoclast and osteoblast want to fix the situation tapi diorang nih tak pandai. So what happened? Formation of involucrum pn happened.

Adoi penat la. So macroscopy plak.
Wut u expected to see?
Of course u will see the involucrum surrounded the infected area. Also u can see sequestra, dead necrotic bodies. What else? Decalcification can also occured.

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